VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch
نویسندگان
چکیده
منابع مشابه
VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch
Aerobic enhanced glycolysis characterizes the Warburg phenotype. In cancer cells, suppression of mitochondrial metabolism contributes to maintain a low ATP/ADP ratio that favors glycolysis. We propose that the voltage-dependent anion channel (VDAC) located in the mitochondrial outer membrane is a metabolic link between glycolysis and oxidative phosphorylation in the Warburg phenotype. Most meta...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2017
ISSN: 2234-943X
DOI: 10.3389/fonc.2017.00004